Stanozolol or Winstrol is the name of an anabolic steroid. The product is available in the form of an oral tablet and an aqueous suspension. Both the forms comprise identical Stanozolol hormone and are C17-aa anabolic steroids. In the market, one can purchase it with a prescription from qualified practitioner. Besides, it is accessible online. It performs an important function, allowing testosterone to exert anabolic activity in muscle tissues by lowering SHBG (Sex Hormone Binding Globulin). Visit Winstrol Results to learn its popularity among the bodybuilders and the athletes.
In sports world, some authorities and bodies has banned the drug following its misuse. Winstrol Results stated its use in veterinary medicine so as to, manage wasting disease, stimulate red blood cells formation, arouse appetite and boost weight gain.
History: An American company, Winthrop Laboratories, first produced Winstrol in 1960s. Food and Drug Administration (FDA), a pharmaceutical medicines and products regulator, analysed the Winstrol’s data to verify its efficacy. The report of FDA came in 1970 and it approved the drug’s application in few treatments including, senile, postmenopausal osteoporosis and pituitary dwarfism and affirmed its use as an adjunct to primary therapy. It’s use won popularity among weight gainers/losers, both men and women, as the side effects of Winstrol was much lower as compared to other drugs. With time, its consumption lowered while alternatives to it increased in market. In 2003, Sanofi sold the business to Ovation Pharmaceuticals. As of today, no other company produce it.
Chemical structure: Winstrol is a modified form of Dihydrotestosterone (DHT). In Winstrol, 3-2 Pyrazol group replaces 3-Keto one attached to the first Cycloalkane ring i.e. A-ring in DHT. This Pyrazol group brings changes in the Winstrol’s anabolic and androgenic strengths. It enhances the former and reduces the latter. A methyl group attached to the 17th carbon proved responsible for the anabolic steroid’ s survival on latter’s first liver passage, when ingested orally.
Winstrol is efficient than DHT because of the following reasons,
- winstrol possess greater active existence in the muscle tissue than DHT
- enzymes in the muscle tissue leave DHT inactive upon its entrance, where no such problem exist in the Winstrol case
Winstrol properties: It possess the ability to lower SHBG, protein that attaches to other sex hormones and makes them ineffective. With few doses, the SHBG reduces to 50% within days, and hence, suppressing its production in the body. In addition to red blood cell count, it enhances protein synthesis and increases nitrogen retention in the muscles. Other properties include,
- ability to bind with cellular androgen receptors
- having small antagonistic effects on Progesterone receptor
- low affinity for Glucocorticoid binding site interaction
- inability to bind with Aromatase enzyme and thus, lowering Estrogen conversion
- inability to interact with 5-alpha Reductase enzyme
At present, though used by fitness enthusiasts in bulk, the doctors and practitioners don’t prescribe it as they used to in past. Also, it is classifies as a controlled substance under the Anabolic Steroids Act of 1990.